Codex becoming unusable for biology and bioinf research?

Hi everyone,

For the past few weeks, especially since GPT-5.6, ChatGPT (work) and Codex have become much less useful for biology, bioinformatics and computational biology research. Even for normal tasks like debugging code, searching papers, summarizing results or discussing analyses, I often get this message:

“This content can’t be shown. We’re especially careful with requests involving biological research and applications that could pose safety risks. Eligible researchers can apply for Trusted Access.”

The problem is that Trusted Access seems to be available only in the US (or difficult for us to achieve as individuals).

Is this happening to other researchers too? Is there any solution? Do you think this will improve, or will researchers need to move to other AI tools?

Thanks!

Welcome to the forum!

Please note that I am not an OpenAI employee—just another user trying to help.

This topic is currently categorized under Codex. OpenAI has recently been changing the names and functionality of several products and features, so I will leave the category as-is for now.

Although many users may be familiar with the Trusted Access application for cybersecurity research, OpenAI also provides a separate application for biology research:

https://openai.com/form/trusted-access-for-biology-research/

I also created the trusted-access-bio tag to make related topics easier to find.

Hopefully, this will help direct more people with relevant experience to this topic who may be able to answer your questions.


Note to regulars: Likes on the original post will help the topic more because our likes carry greater weight and are more effective when applied to the first post. Thanks.

Thanks for reaching out and sharing your experience @csernab

OpenAI offers a separate Trusted Access for Biology Research program for eligible researchers. You can find more information and apply here

Hopefully this helps!

~ Smith