Can I order Assistant to use specific files for answers?

Hi,
I configured Assistant, uploaded files. Assistant uses vector database.

  1. Can I, via Assistant instructions limit the files it should use as it’s knowledge for specific question? The problem is that sometimes extensions document overwrites information from base instruction and I would like to avoid the confusing answers.

For example, something like this:
Instructions:

  • at the beginning of each conversation, always ask user if he is wants only base instruction or specific extensions. For base instructions use only files starting with Base_ .
  1. If not, I understand I would need to define 2 vector databases, one containing base_instructions and second containing all data and select it via API depending on user choices? Correct?