you do not need to give it new instruction. you can use the original instruction in every thread you make. however, you can also extend its instruction to append “new instruction” depending on the circumstances (e.g. append current datetime, user profile, etc.). you can use the assistant like a stand-alone API endpoint (1 call 1 result) or as normal chatbot. you can make an assistant with base instruction, base knowledge files and just extend it per user.
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