Assistant RAG file management strategy: Many chunks or many files?

I just stumbled over this in the documentation:

“Ensuring vector store readiness before creating runs”

…We highly recommend that you ensure all files in a vector_store are fully processed before you create a run. This will ensure that all the data in your vector_store is searchable. You can check for vector_store readiness by using the polling helpers in our SDKs, or by manually polling the vector_store object to ensure the status is completed…

https://platform.openai.com/docs/assistants/tools/file-search#ensuring-vector-store-readiness-before-creating-runs